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Nicolle provides an update on Serious Skincare's Insta-Tox Instant Wrinkle Eradicator in her video review. She praises the product, mentioning that it is a great skincare solution. Nicolle demonstrates the product's effectiveness by applying a small amount to one side of her face, showcasing the noticeable difference in her eye area. The treated side appears lifted and more open, giving her a cat-eye effect. She emphasizes that these results are instant and highly recommends trying Insta-Tox. Overall, Nicolle's review highlights the product's ability to deliver immediate and visible results, making it a must-have for anyone looking to reduce wrinkles and achieve a more youthful appearance.