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The Large Lash Serum by Pixi is the focus of Ashlie's initial review. She mentions that the serum is smaller than expected, but the applicator is easy to use. Ashlie applies the serum to her lashes, including the lower ones, and notes that it is sensitive eyeball approved. She advises against getting the serum directly in the eye as it may cause irritation. After about 10 minutes, Ashlie concludes that the serum is gentle and does not cause any discomfort. Overall, the Large Lash Serum by Pixi seems to be a promising product for those looking to enhance their lashes without any irritation.