The best way to kickstart the day! I had no idea what L -Methylfolate was until I researched it more I realize that other people might not know this too I was mind blown by the benefits I was missing out on from not taking this supplement until recently. Essentially it’s a combination of folate also known as B9 and B12. Those with the MTHR gene may experience the inability to absorb folate. This can lead to other things such as anemia because low folate can impact your ability to absorb iron. Specifically with L -Methyfolate it creates methylation which is a process where a methyl group adds to DNA proteins and other molecules to assist with nutrient delivery. Now even if you don t have the MTHFR gene mutation, other conditions can also cause low folate levels.